Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.44 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30708251 | 0.84 | CD274 (0.54) | ALDH1A1KDM4ETDP1SLC6A2SLC6A4 | |
| SCHEMBL29955849 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL21345583 | 0.82 | LMNA (0.47) | ALDH1A1KDM4ETDP1SLC6A2SLC6A4 | |
| SCHEMBL27700419 | 0.78 | ADRB2 (0.48) | ALDH1A1TDP1MEN1KMT2ANPSR1 | |
| SCHEMBL11017578 | 0.78 | LDHA (0.55) | ALDH1A1TDP1MEN1KMT2ANPSR1 | |
| SCHEMBL27471328 | 0.78 | CD274 (0.57) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL20738591 | 0.77 | SETDB1 (0.53) | ALDH1A1SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL29589093 | 0.76 | CD274 (0.61) | MEN1KMT2ACD274LMNA | |
| SCHEMBL29589384 | 0.76 | CD274 (0.61) | MEN1KMT2ACD274LMNA | |
| SCHEMBL20582100 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117561246-A | Novel biphenyl derivative, preparation method and medical application thereof | 西安新通药物研究股份有限公司 | 2024-02-13 | — | — | CN | disclosed |