Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31320036 | 0.95 | NAAA (0.51) | HTTTSHRHPGDSMN1; SMN2HDAC3 | |
| SCHEMBL3983398 | 0.92 | L3MBTL1 (0.49) | HTTTSHRHPGDTMEM97SIGMAR1 | |
| SCHEMBL29957324 | 0.89 | TSHR (0.53) | HTTTSHRHPGDSMN1; SMN2HDAC3 | |
| SCHEMBL29954265 | 0.85 | LMNA (0.42) | HPGDHDAC1TMEM97SIGMAR1L3MBTL1 | |
| SCHEMBL13644472 | 0.84 | MAOB (0.41) | TSHRHDAC3TMEM97SIGMAR1NPC1 | |
| SCHEMBL14743123 | 0.84 | MAP2K2 (0.47) | HTTHPGDTMEM97SIGMAR1NPC1 | |
| SCHEMBL12693827 | 0.83 | HDAC6 (0.41) | TSHRHPGDHDAC3HDAC1NAAA | |
| SCHEMBL15798271 | 0.83 | HDAC6 (0.46) | HTTSMN1; SMN2HDAC3HDAC1LMNA | |
| Hydrochloric Acid SCHEMBL23827734 | 0.83 | PMP22 (0.42) | TSHRHDAC3TMEM97SIGMAR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30152034 | 0.83 | PMP22 (0.42) | TSHRHDAC3TMEM97SIGMAR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |