Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951399 | 0.92 | POLB (0.39) | POLBKAT2BBAZ2BCNR2KDM4E | |
| SCHEMBL29957502 | 0.84 | KMO (0.45) | POLBKDM4EPDE4APDE4BPDE4C | |
| SCHEMBL29955972 | 0.83 | PDE4A (0.46) | POLBGPR6HRH3PDE4APDE4B | |
| SCHEMBL29955501 | 0.78 | POLB (0.43) | POLB | |
| SCHEMBL29953007 | 0.78 | KAT2B (0.43) | KAT2BBAZ2BEPHX2PDE4APDE4B | |
| SCHEMBL29956377 | 0.77 | KAT2B (0.39) | POLBKAT2BBAZ2BEPHX2PDE4A | |
| SCHEMBL29955295 | 0.76 | KAT2B (0.44) | POLBKAT2BBAZ2BPDE4APDE4B | |
| SCHEMBL29951840 | 0.75 | POLB (0.42) | POLBKDM4EALDH1A1PDE4APDE4B | |
| SCHEMBL29953202 | 0.74 | KMO (0.44) | POLBKDM4EPDE4APDE4BPDE4C | |
| SCHEMBL30108322 | 0.74 | MAPT (0.42) | BAZ2BKDM4ENPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |