Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560739 | 0.86 | MAPT (0.65) | SMN1; SMN2RAB9APTGDR2KMT2AHPGD | |
| SCHEMBL29954842 | 0.84 | KMT2A (0.59) | SMN1; SMN2RAB9AKMT2AHPGDALDH1A1 | |
| SCHEMBL29955221 | 0.82 | PTGDR2 (0.62) | SMN1; SMN2RAB9APTGDR2KMT2AHPGD | |
| SCHEMBL2563006 | 0.81 | ALDH1A1 (0.71) | SMN1; SMN2RAB9AHPGDALDH1A1HTT | |
| SCHEMBL7365741 | 0.81 | PTGDR2 (0.60) | SMN1; SMN2RAB9APTGDR2KMT2AHPGD | |
| SCHEMBL9275347 | 0.81 | SMN1; SMN2 (0.72) | SMN1; SMN2RAB9AKMT2AHPGDALDH1A1 | |
| SCHEMBL2558036 | 0.80 | PTGDR2 (0.59) | SMN1; SMN2RAB9APTGDR2KMT2AHPGD | |
| SCHEMBL15332808 | 0.80 | PTGDR2 (0.59) | SMN1; SMN2RAB9APTGDR2KMT2AHPGD | |
| SCHEMBL2562735 | 0.79 | PTGDR2 (0.67) | SMN1; SMN2RAB9APTGDR2KMT2AHPGD | |
| SCHEMBL24590651 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9AKMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |