Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5856821 | 0.81 | CA2 (0.48) | ALDH1A1ACHEPOLBCYP2C9MAPK1 | |
| SCHEMBL12659805 | 0.78 | ACHE (0.40) | ALDH1A1MAPTSMN1; SMN2ALOX15GAA | |
| SCHEMBL12024940 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10019233 | 0.76 | TUBB1 (0.47) | ALDH1A1MAPTMEN1KMT2AALOX15 | |
| SCHEMBL29955166 | 0.76 | SLC1A5 (0.40) | — | |
| SCHEMBL9672417 | 0.74 | MAPT (0.38) | ALDH1A1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29954325 | 0.73 | LRRK2 (0.35) | ACHELRRK2 | |
| SCHEMBL11959890 | 0.73 | ACHE (0.35) | ALDH1A1MAPTACHELRRK2 | |
| SCHEMBL2916024 | 0.73 | AHR (0.43) | ALDH1A1HSD17B10MAPK1TP53 | |
| SCHEMBL12024943 | 0.73 | TAAR1 (0.42) | ALDH1A1MEN1KMT2AHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |