Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.67 |
| ▸ | HTR1A | P08908 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | HTR1D | P28221 | 2/20 | 0.56 |
| ▸ | HTR1B | P28222 | 2/20 | 0.56 |
| ▸ | HTR1F | P30939 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15757545 | 1.00 | HTR6 (0.67) | HTR6HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL31092832 | 0.89 | HTR6 (0.58) | HTR6HTR1ADRD2HTR2AHTT | |
| SCHEMBL16916800 | 0.83 | PIK3C3 (0.53) | HTR6HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL819444 | 0.82 | LMNA (0.62) | HTR6HTR1ADRD2DRD3HTR1D | |
| SCHEMBL29737165 | 0.82 | LMNA (0.62) | HTR6HTR1ADRD2DRD3HTR1D | |
| SCHEMBL5758119 | 0.80 | HTR6 (1.00) | HTR6HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL3621599 | 0.80 | HTR6 (0.68) | HTR6HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL4023835 | 0.79 | HTR6 (0.67) | HTR6HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL4029770 | 0.78 | HTR6 (0.72) | HTR6HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL27849149 | 0.78 | HTR6 (0.68) | HTR6HTR1ADRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |