Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2560168 | 0.87 | IDO1 (0.36) | ERN1ALDH1A1KDM4EMAPTSLC6A4 | |
| SCHEMBL29954725 | 0.86 | ICMT (0.35) | ERN1ALDH1A1 | |
| SCHEMBL2563489 | 0.86 | ERN1 (0.39) | ERN1ALDH1A1KDM4EMPOMAPT | |
| SCHEMBL2556059 | 0.81 | ERN1 (0.35) | ERN1ALDH1A1KDM4EMAPTDPP9 | |
| SCHEMBL29952046 | 0.79 | JAK2 (0.37) | ERN1ALDH1A1MAPTDPP9 | |
| SCHEMBL29955172 | 0.78 | TDP1 (0.41) | ERN1ALDH1A1PTPN1KEAP1 | |
| SCHEMBL29952786 | 0.76 | ALDH1A3 (0.40) | ERN1ALDH1A1KDM4E | |
| SCHEMBL29950882 | 0.75 | ALDH1A3 (0.39) | ERN1ALDH1A1KDM4EMPOMAPT | |
| SCHEMBL29955288 | 0.74 | ALDH1A3 (0.38) | ERN1ALDH1A1KDM4EMPOMAPT | |
| SCHEMBL2554833 | 0.73 | ALDH1A1 (0.39) | ERN1ALDH1A1KDM4EMPOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |