Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ASPH | Q12797 | 2/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456606 | 1.00 | HCAR2 (0.52) | HCAR2MEN1KMT2AKDM4ENAPRT | |
| Water SCHEMBL9818035 | 0.98 | HCAR2 (0.50) | HCAR2MEN1KMT2AKDM4ENAPRT | |
| SCHEMBL944797 | 0.82 | ADORA3 (0.44) | HCAR2MEN1KMT2ALMNATSHR | |
| SCHEMBL18104371 | 0.82 | ALDH1A1 (0.44) | HCAR2MEN1KMT2AALDH1A1 | |
| SCHEMBL1134519 | 0.77 | CNR1 (0.41) | HCAR2MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL3456871 | 0.74 | CYP1A2 (0.46) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL9422314 | 0.72 | — | — | |
| SCHEMBL9422315 | 0.72 | CNR2 (0.31) | KDM4ELMNASMN1; SMN2TDP1 | |
| SCHEMBL9617684 | 0.69 | — | — | |
| Acipimox SCHEMBL6057382 | 0.68 | HCAR2 (1.00) | HCAR2MEN1KMT2AKDM4ENAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |