Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2005193 | 0.75 | BRD4 (0.42) | BRD4SMN1; SMN2HIF1A | |
| SCHEMBL20871562 | 0.69 | BRD4 (0.41) | BRD4 | |
| SCHEMBL2736863 | 0.69 | CYP3A4 (0.44) | BRD4SMN1; SMN2HIF1A | |
| SCHEMBL21026104 | 0.69 | BRD4 (0.42) | BRD4 | |
| SCHEMBL21807206 | 0.69 | LMNA (0.41) | BRD4TP53SMN1; SMN2HIF1A | |
| SCHEMBL24399382 | 0.69 | BRD4 (0.42) | BRD4SMN1; SMN2 | |
| SCHEMBL30712749 | 0.69 | BRD4 (0.60) | BRD4TP53HIF1A | |
| SCHEMBL2399704 | 0.69 | MAPT (0.44) | ENPP2 | |
| SCHEMBL29595177 | 0.69 | MAPT (0.44) | ENPP2 | |
| SCHEMBL2330838 | 0.68 | MAOA (0.41) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |