Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16377909 | 0.78 | KDM4E (0.39) | KDM4ELMNATOP2AL3MBTL1ALOX12 | |
| SCHEMBL16856823 | 0.74 | LMNA (0.44) | KDM4ELMNATOP2AL3MBTL1CETP | |
| SCHEMBL7125030 | 0.72 | L3MBTL1 (0.41) | KDM4ELMNATOP2AL3MBTL1CETP | |
| SCHEMBL22500987 | 0.71 | TOP2A (0.48) | KDM4ELMNATOP2AL3MBTL1ALOX12 | |
| SCHEMBL13524441 | 0.70 | KDM4E (0.40) | KDM4ELMNAL3MBTL1ALOX12CETP | |
| SCHEMBL29958183 | 0.69 | L3MBTL1 (0.38) | KDM4ELMNATOP2AL3MBTL1ALOX12 | |
| SCHEMBL3148153 | 0.69 | LMNA (0.41) | KDM4ELMNAL3MBTL1ALOX12CETP | |
| SCHEMBL16857291 | 0.69 | TOP2A (0.38) | KDM4ELMNATOP2AL3MBTL1CETP | |
| SCHEMBL16857151 | 0.69 | TOP2A (0.38) | KDM4ELMNATOP2AL3MBTL1CETP | |
| SCHEMBL22208034 | 0.69 | LMNA (0.45) | KDM4ELMNATOP2AL3MBTL1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |