Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954919 | 0.92 | KCNH2 (0.38) | KDM4EALDH1A1TLR4HPGDHTT | |
| SCHEMBL29953182 | 0.87 | ALDH1A1 (0.36) | KDM4EALDH1A1TLR4MEN1MAPT | |
| SCHEMBL15331758 | 0.86 | L3MBTL1 (0.33) | KDM4EALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL1224692 | 0.79 | ALOX5AP (0.31) | KMT2AALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL718784 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL29951760 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL15912964 | 0.77 | ALOX5AP (0.51) | KDM4EMEN1MAPTHPGDKMT2A | |
| SCHEMBL28472673 | 0.75 | KDM4E (0.39) | KDM4EALDH1A1MEN1MAPTHPGD | |
| SCHEMBL29952801 | 0.73 | — | — | |
| SCHEMBL15912973 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |