Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956099 | 0.92 | KDM4E (0.35) | KCNH2HTTTLR4KDM4ESMN1; SMN2 | |
| SCHEMBL29953182 | 0.85 | ALDH1A1 (0.36) | HTTTLR4KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL15331758 | 0.84 | L3MBTL1 (0.33) | KDM4ERAB9AHPGDALDH1A1TDP1 | |
| SCHEMBL3837368 | 0.79 | THRA (0.43) | KCNH2HTTRECQLTLR4KDM4E | |
| SCHEMBL15564717 | 0.78 | NR5A1 (0.40) | TLR4THRATHRBLTA4HNR5A1 | |
| SCHEMBL1224692 | 0.78 | ALOX5AP (0.31) | SMN1; SMN2 | |
| SCHEMBL3982711 | 0.78 | KDM4E (0.45) | KCNH2KDM4EESR1RAB9AHPGD | |
| SCHEMBL718784 | 0.76 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL29951760 | 0.76 | ALDH1A1 (0.43) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL15912964 | 0.76 | ALOX5AP (0.51) | KDM4ETHRATHRBSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |