Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PRF1 | P14222 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2501696 | 0.92 | PRF1 (0.44) | LMNAPARP1HTTPARP2PRF1 | |
| SCHEMBL29956886 | 0.89 | ALDH1A1 (0.42) | LMNAPARP1HTTPARP2PRF1 | |
| SCHEMBL29955396 | 0.88 | PRF1 (0.40) | PRF1GRM5GRM1KDM4ETSHR | |
| SCHEMBL2559421 | 0.87 | PRF1 (0.43) | PARP1PARP2PRF1KDM4ETSHR | |
| SCHEMBL2627975 | 0.81 | PARP1 (0.47) | PARP1PARP2KDM4ETSHRALOX15 | |
| SCHEMBL289469 | 0.80 | UGCG (0.39) | PARP1PRF1GRM5 | |
| SCHEMBL29431366 | 0.80 | UGCG (0.39) | PARP1PRF1GRM5 | |
| SCHEMBL29955702 | 0.80 | ENPP2 (0.36) | PRF1KDM4ETSHRALOX15SIRT1 | |
| SCHEMBL1500127 | 0.78 | PRF1 (0.44) | LMNAPARP1HTTPARP2PRF1 | |
| SCHEMBL4724309 | 0.78 | KDM4E (0.48) | LMNAPARP1HTTPARP2PRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |