Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950950 | 0.85 | NPC1 (0.49) | ALDH1A1LMNANPC1KDM4EL3MBTL1 | |
| SCHEMBL29956360 | 0.78 | ALDH1A1 (0.36) | ALDH1A1LMNANPC1L3MBTL1MAPT | |
| SCHEMBL671732 | 0.76 | — | — | |
| SCHEMBL28658619 | 0.76 | KDM4E (0.37) | ALDH1A1NPC1KDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL4915942 | 0.74 | SMN1; SMN2 (0.45) | ALDH1A1LMNANPC1KDM4EL3MBTL1 | |
| SCHEMBL15332377 | 0.72 | LMNA (0.44) | ALDH1A1LMNANPC1KDM4EL3MBTL1 | |
| SCHEMBL4427300 | 0.69 | DGAT1 (0.34) | ALDH1A1LMNANPC1KDM4E | |
| SCHEMBL19369013 | 0.68 | LMNA (0.33) | ALDH1A1LMNANPC1KDM4EPRKDC | |
| SCHEMBL20254196 | 0.68 | ALDH1A1 (0.35) | ALDH1A1LMNANPC1KDM4EL3MBTL1 | |
| SCHEMBL23497963 | 0.67 | CYP2A6 (0.41) | ALDH1A1KDM4EALDH1A3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |