Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3292146 | 1.00 | HPGD (0.46) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL27400684 | 0.88 | HPGD (0.46) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL29950861 | 0.88 | HPGD (0.46) | HPGDCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL29956545 | 0.87 | MIF (0.43) | HPGDCYP1A2CYP2C9CYP2C19CA12 | |
| SCHEMBL29954656 | 0.87 | KCNQ4 (0.46) | CA12CA1CA9BRD9CYP17A1 | |
| SCHEMBL5425869 | 0.87 | CA12 (0.49) | CA12CA1CA9CYP17A1RXFP1 | |
| SCHEMBL8140376 | 0.85 | NPC1 (0.45) | SMN1; SMN2CYP17A1KMT2AMAPTPOLB | |
| SCHEMBL16802013 | 0.85 | HSP90AA1 (0.43) | CA12CA1CA9CYP17A1RXFP1 | |
| SCHEMBL29954247 | 0.84 | ERN1 (0.49) | HPGDCYP1A2KDM4EALDH1A1GAA | |
| SCHEMBL21639702 | 0.83 | ERN1 (0.44) | HPGDSMN1; SMN2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |