Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3292146 | 0.87 | HPGD (0.46) | RXFP1CYP17A1CA12CA1CA9 | |
| SCHEMBL29956441 | 0.87 | HPGD (0.46) | RXFP1CYP17A1CA12CA1CA9 | |
| SCHEMBL5425869 | 0.85 | CA12 (0.49) | RXFP1CYP17A1CA12CA1CA9 | |
| SCHEMBL29954656 | 0.85 | KCNQ4 (0.46) | RXFP1ATRCYP17A1CA12CA1 | |
| SCHEMBL8140376 | 0.84 | NPC1 (0.45) | CYP17A1POLBMAPTKMT2AKDM4E | |
| SCHEMBL16802013 | 0.84 | HSP90AA1 (0.43) | RXFP1ATRCYP17A1CA12CA1 | |
| SCHEMBL29954247 | 0.83 | ERN1 (0.49) | ALDH1A1KDM4ECYP1A2HPGDNPC1 | |
| SCHEMBL24362149 | 0.83 | HPGD (0.47) | MIFRXFP1ATRNQO2CYP17A1 | |
| SCHEMBL29618957 | 0.83 | HPGD (0.47) | MIFRXFP1ATRNQO2CYP17A1 | |
| SCHEMBL21639702 | 0.82 | ERN1 (0.44) | ATRCYP17A1CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |