Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8764571 | 0.87 | CCR1 (0.53) | CCR1CCR5CCR8PARP1MEN1 | |
| Formamide SCHEMBL9731312 | 0.82 | ESR2 (0.47) | PARP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9731308 | 0.79 | MAPT (0.56) | PARP1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL27756977 | 0.78 | CCR1 (0.50) | CCR1CCR5CCR8PARP1MEN1 | |
| SCHEMBL3252945 | 0.78 | NR4A2 (0.58) | CCR1CCR5CCR8PARP1MEN1 | |
| SCHEMBL24956766 | 0.78 | HTR1A (0.51) | CCR1CCR5CCR8PARP1MEN1 | |
| SCHEMBL2326429 | 0.78 | CCR1 (0.50) | CCR1CCR5CCR8PARP1MEN1 | |
| SCHEMBL9034955 | 0.78 | SLC22A12 (0.50) | CCR1CCR5CCR8ALDH1A1LMNA | |
| SCHEMBL20732994 | 0.78 | CCR1 (0.50) | CCR1CCR5CCR8PARP1MEN1 | |
| SCHEMBL29955156 | 0.77 | RAB9A (0.46) | CCR1CCR5CCR8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |