SCHEMBL8764571

SCHEMBL8764571

O=Cc1ccnc2cc(O)ccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 1/20 0.53
CCR5 P51681 1/20 0.53
CCR8 P51685 1/20 0.53
TLR8 Q9NR97 1/20 0.44
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
MAPT P10636 4/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 2/20 0.44
LMNA P02545 1/20 0.44
CASP3 P42574 1/20 0.44
HTT P42858 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
KDM4E B2RXH2 4/20 0.44
NPSR1 Q6W5P4 2/20 0.44
NPC1 O15118 1/20 0.44
HSP90AA1 P07900 1/20 0.44
IDO1 P14902 1/20 0.44
RAB9A P51151 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29956482 0.87 CCR1 (0.50) CCR1CCR5CCR8MEN1KMT2A
Formamide SCHEMBL9730946 0.82 TLR8 (0.40) CCR1CCR5CCR8TLR8MEN1
SCHEMBL9730944 0.80 MAPT (0.55) CCR1CCR5CCR8TLR8MEN1
SCHEMBL1496369 0.79 CCR1 (0.53) CCR1CCR5CCR8ALDH1A1HTT
SCHEMBL11744477 0.79 CCR1 (0.53) CCR1CCR5CCR8MEN1KMT2A
SCHEMBL3709985 0.79 NR4A2 (0.56) CCR1CCR5CCR8MEN1KMT2A
SCHEMBL29954354 0.77 ERN1 (0.54) CCR1CCR5CCR8MEN1KMT2A
SCHEMBL29509132 0.75 TLR8 (0.54) TLR8MEN1KMT2AMAPTALDH1A1
SCHEMBL28164080 0.75 TLR8 (0.54) TLR8MEN1KMT2AMAPTALDH1A1
SCHEMBL2933117 0.75 KDM4E (0.55) CCR1CCR5CCR8TLR8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620918-B1 CARBON DIOXIDE DETECTOR JOHNSON & JOHNSON PROFESSIONAL (GB) 1997-07-30 EP claimed
US-5480611-A Carbon dioxide detector GE MEDICAL SYSTEMS INFORMATION TECHNOLOGIES, INC. 1996-01-02 US claimed
EP-0620918-A1 CARBON DIOXIDE DETECTOR. JOHNSON & JOHNSON PROFESSIONAL (GB) 1994-10-26 EP claimed
WO-1993014399-A1 CARBON DIOXIDE DETECTOR JOHNSON & JOHNSON PROFESSIONAL PRODUCTS LTD. (GB) 1993-07-22 WO claimed
EP-3721193-B1 METHOD OF PRODUCING A COLOR CHANGEABLE POLYMERIC COMPOSITE THERMOGRAPHIC MEASUREMENTS LTD (GB) 2024-03-27 EP disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-11346786-B2 High pressure sensitive color changeable indicators and methods of making such indicators SENSOR INTERNATIONAL, LLC (US) 2022-05-31 US disclosed
EP-3863862-A1 HIGH PRESSURE SENSITIVE COLOR CHANGEABLE INDICATORS AND METHODS OF MAKING SUCH INDICATORS Sensor International, LLC (US) 2021-08-18 EP disclosed
EP-3721193-A1 MELTABLE COLOR CHANGEABLE INDICATORS WITH ORGANIC POLYMER CORES AND METHODS OF MAKING SUCH MELTABLE INDICATORS AND COMPOSITES THEREOF Sensor International, LLC (US) 2020-10-14 EP disclosed
US-10759976-B2 Color changeable adhesives and methods of making such adhesives SENSOR INTERNATIONAL, LLC (US) 2020-09-01 US disclosed
US-20200110036-A1 HIGH PRESSURE SENSITIVE COLOR CHANGEABLE INDICATORS AND METHODS OF MAKING SUCH INDICATORS BARINGS FINANCE LLC 2020-04-09 US disclosed
US-20190292421-A1 COLOR CHANGEABLE ADHESIVES AND METHODS OF MAKING SUCH ADHESIVES BARINGS FINANCE LLC 2019-09-26 US disclosed
WO-2019113148-A1 MELTABLE COLOR CHANGEABLE INDICATORS WITH ORGANIC POLYMER CORES AND METHODS OF MAKING SUCH MELTABLE INDICATORS AND COMPOSITES THEREOF SENSOR INTERNATIONAL, LLC (US) 2019-06-13 WO disclosed
US-20190170714-A1 MELTABLE COLOR CHANGEABLE INDICATORS WITH ORGANIC POLYMER CORES AND METHODS OF MAKING SUCH MELTABLE INDICATORS AND COMPOSITES THEREOF BARINGS FINANCE LLC 2019-06-06 US disclosed
EP-0620918-B1 CARBON DIOXIDE DETECTOR JOHNSON & JOHNSON PROFESSIONAL (GB) 1997-07-30 EP disclosed
US-5480611-A Carbon dioxide detector GE MEDICAL SYSTEMS INFORMATION TECHNOLOGIES, INC. 1996-01-02 US disclosed
EP-0620918-A1 CARBON DIOXIDE DETECTOR. JOHNSON & JOHNSON PROFESSIONAL (GB) 1994-10-26 EP disclosed
WO-1993014399-A1 CARBON DIOXIDE DETECTOR JOHNSON & JOHNSON PROFESSIONAL PRODUCTS LTD. (GB) 1993-07-22 WO disclosed