Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.34 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.34 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526340 | 0.78 | KDM4C (0.50) | ERN1TDP1SIRT3MAPTCCNC | |
| SCHEMBL29956489 | 0.78 | KDM4C (0.50) | ERN1TDP1SIRT3MAPTCCNC | |
| SCHEMBL16217237 | 0.77 | TDP1 (0.43) | ERN1TDP1SIRT3MAPTCCNC | |
| SCHEMBL31146203 | 0.75 | KDM4E (0.47) | TDP1SIRT3MAPTGSK3BNPC1 | |
| SCHEMBL15780388 | 0.74 | CES1 (0.47) | ERN1TDP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL5834304 | 0.72 | ALDH1A1 (0.56) | ERN1TDP1SIRT3POLBKDM4E | |
| SCHEMBL14097049 | 0.72 | NUDT1 (0.44) | TDP1SIRT3CCNCCDK8KDM4E | |
| SCHEMBL3451540 | 0.71 | SIRT3 (0.39) | TDP1SIRT3MAPTGSK3BNPC1 | |
| SCHEMBL30800801 | 0.71 | ERN1 (0.48) | ERN1NPC1POLBKDM4CCCNT1 | |
| SCHEMBL9274800 | 0.71 | ERN1 (0.48) | ERN1NPC1POLBKDM4CCCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265220-B1 | NON-IMMUNOCHEMICAL METHOD BY REACTING A COMPOUND COMPRISING CIS-1,4-DIOXO-2-BUTENE MOIETY OR HYDROLYTICALLY DERIVED PRECURSOR WITH HOMOCYSTEINE, THEN DETECTING PRODUCT WITHOUT SEPARATION FROM LIQUID | ULLMAN EDWIN F (US) | 2001-07-24 | — | — | US | disclosed |
| WO-2000000821-A1 | ASSAY FOR HOMOCYSTEINE | ULLMAN EDWIN F (US) | 2000-01-06 | — | — | WO | disclosed |