Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CLPP | Q16740 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047592 | 1.00 | ALDH1A1 (0.50) | ALDH1A1GAACLPPALOX5TTR | |
| SCHEMBL29952586 | 0.88 | PSMB5 (0.44) | ALDH1A1GAAALOX5SMN1; SMN2PSMB5 | |
| SCHEMBL248676 | 0.82 | TTR (0.44) | ALDH1A1GAATTRALOX15NPC1 | |
| SCHEMBL13717846 | 0.81 | ALOX5 (0.42) | ALDH1A1GAAALOX5PSMB5POLB | |
| SCHEMBL13754447 | 0.80 | ALDH1A1 (0.72) | ALDH1A1GAAALOX15NPC1RAB9A | |
| SCHEMBL29956493 | 0.79 | MAPT (0.64) | ALDH1A1GAATTRNPC1RAB9A | |
| SCHEMBL364081 | 0.79 | ABL1 (0.47) | ALDH1A1GAATTRSMN1; SMN2MAPT | |
| SCHEMBL29950902 | 0.79 | ABL1 (0.47) | ALDH1A1GAATTRSMN1; SMN2MAPT | |
| SCHEMBL4063989 | 0.78 | ALOX5 (0.42) | ALDH1A1GAAALOX5PSMB5 | |
| SCHEMBL4043611 | 0.78 | POLB (0.54) | ALDH1A1GAATTRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |