Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124629 | 1.00 | RAD51 (0.42) | RAD51CA1CA2KIF11GABRP | |
| SCHEMBL31124554 | 0.89 | FFAR1 (0.36) | RAD51KIF11P4HBERN1 | |
| SCHEMBL29956520 | 0.84 | RAD51 (0.39) | RAD51CA1CA2KIF11HSD17B14 | |
| SCHEMBL921358 | 0.84 | RAD51 (0.39) | RAD51CA1CA2KIF11HSD17B14 | |
| SCHEMBL29642158 | 0.81 | RAD51 (0.40) | RAD51CA1CA2KIF11HSD17B14 | |
| SCHEMBL23835197 | 0.80 | RAD51 (0.39) | RAD51KIF11PIN1MEN1KMT2A | |
| SCHEMBL1165506 | 0.80 | ERN1 (0.34) | CA1CA2MEN1KMT2AERN1 | |
| SCHEMBL31159880 | 0.80 | RAD51 (0.39) | RAD51KIF11PIN1MEN1KMT2A | |
| SCHEMBL4680994 | 0.79 | RAD51 (0.40) | RAD51CA1CA2PIN1MEN1 | |
| SCHEMBL4680996 | 0.79 | RAD51 (0.40) | RAD51CA1CA2PIN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |