Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 2/20 | 0.40 |
| ▸ | P4HB | P07237 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680996 | 1.00 | RAD51 (0.40) | RAD51P4HBCA1CA2MIF | |
| SCHEMBL124629 | 0.79 | RAD51 (0.42) | RAD51P4HBCA1CA2MEN1 | |
| SCHEMBL29956507 | 0.79 | RAD51 (0.42) | RAD51P4HBCA1CA2MEN1 | |
| SCHEMBL7810204 | 0.78 | NFE2L2 (0.53) | NFE2L2KCNH2 | |
| SCHEMBL7810200 | 0.78 | NFE2L2 (0.53) | NFE2L2KCNH2 | |
| SCHEMBL6708260 | 0.74 | MIF (0.61) | RAD51P4HBCA1CA2MIF | |
| SCHEMBL6708257 | 0.74 | MIF (0.61) | RAD51P4HBCA1CA2MIF | |
| SCHEMBL17296534 | 0.73 | RAD51 (0.41) | RAD51P4HBCA1CA2MEN1 | |
| SCHEMBL17296535 | 0.73 | RAD51 (0.41) | RAD51P4HBCA1CA2MEN1 | |
| SCHEMBL5554957 | 0.73 | MIF (0.44) | RAD51P4HBMIFMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010035766-A1 | METHOD FOR PRODUCING TRIAZOLE DERIVATIVE | 第一三共株式会社 (JP) | 2010-04-01 | — | — | WO | disclosed |
| EP-1362856-B1 | WATER-SOLUBLE TRIAZOLE FUNGICIDE | DAIICHI SANKYO CO LTD (JP) | 2008-09-10 | — | — | EP | disclosed |
| US-7230023-B2 | Water-soluble triazole fungicide | SANKYO COMPANY, LIMITED (JP) | 2007-06-12 | — | — | US | disclosed |
| US-20040198790-A1 | Water-soluble triazole fungicide | SANKYO COMPANY, LIMITED (JP) | 2004-10-07 | — | — | US | disclosed |
| EP-1362856-A1 | WATER-SOLUBLE TRIAZOLE FUNGICIDE | Sankyo Company, Limited (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1083175-B1 | Triazole derivatives having antifungal activity | SANKYO CO (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6392082-B1 | CHEMICAL INTERMEDIATE | SANKYO COMPANY, LIMITED (JP) | 2002-05-21 | — | — | US | disclosed |
| US-6391903-B1 | THERAPY FOR FUNGI INFECTIONS | SANKYO COMPANY, LIMITED (JP) | 2002-05-21 | — | — | US | disclosed |
| US-6337403-B1 | CRYSTALLINE FORM OF A PHARMACEUTICAL COMPOSITION CONTAINING SAID DERIVATIVES WITH TREATING AND PREVENTING FUNGAL INFECTIONS USING BUTADIENE FLUORO BENZONITRILE GROUPS | SANKYO COMPANY, LIMITED (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-1083175-A2 | Triazole derivatives having antifungal activity | Sankyo Company Limited (JP) | 2001-03-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198790-A1 | Water-soluble triazole fungicide | ERG28, CYP51A1, XDH | RAD51 4821/4885P4HB 331/4885CA1 864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.