SCHEMBL124629

SCHEMBL124629

N#Cc1ccc(C=O)c(F)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAD51 Q06609 1/20 0.42
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
KIF11 P52732 1/20 0.36
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
GABRA2 P47869 1/20 0.36
GABRB2 P47870 1/20 0.36
GABRA4 P48169 1/20 0.36
GABRE P78334 1/20 0.36
GABRA6 Q16445 1/20 0.36
GABRG1 Q8N1C3 1/20 0.36
GABRG3 Q99928 1/20 0.36
GABRQ Q9UN88 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29956507 1.00 RAD51 (0.42) RAD51CA1CA2KIF11GABRP
SCHEMBL31124554 0.89 FFAR1 (0.36) RAD51KIF11P4HBERN1
SCHEMBL29956520 0.84 RAD51 (0.39) RAD51CA1CA2KIF11HSD17B14
SCHEMBL921358 0.84 RAD51 (0.39) RAD51CA1CA2KIF11HSD17B14
SCHEMBL29642158 0.81 RAD51 (0.40) RAD51CA1CA2KIF11HSD17B14
SCHEMBL23835197 0.80 RAD51 (0.39) RAD51KIF11PIN1MEN1KMT2A
SCHEMBL1165506 0.80 ERN1 (0.34) CA1CA2MEN1KMT2AERN1
SCHEMBL31159880 0.80 RAD51 (0.39) RAD51KIF11PIN1MEN1KMT2A
SCHEMBL4680994 0.79 RAD51 (0.40) RAD51CA1CA2PIN1MEN1
SCHEMBL4680996 0.79 RAD51 (0.40) RAD51CA1CA2PIN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 402 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107227-A1 COMPOSITIONS COMPRISING USP1 INHIBITORS AND METHODS OF USING THE SAME EIKON THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
US-12611401-B2 Combinations comprising benzodioxol as GLP-1R agonists for use in the treatment of NASH/NAFLD and related diseases PFIZER INC. (US) 2026-04-28 US disclosed
EP-4706757-A2 2-(((2,3-DIHYDROBENZO[B][1,4]DIOXAN-5-YL)PIPERIDIN-1-YL)METHYL)-1-((OXETAN-2-YL)METHYL)-1H-BENZO[D]IMIDAZOLE-6-CARBOXYLIC ACID DERIVATIVES AND SIMILAR COMPOUNDS AS GLP-1 MODULATORS FOR THE TREATMENT OF DIABETES Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2026-03-11 EP disclosed
EP-4209490-B1 2-(((2,3-DIHYDROBENZO[B][1,4]DIOXAN-5-YL)PIPERIDIN-1-YL)METHYL)-1-((OXETAN-2-YL)METHYL)-1H-BENZO[D]IMIDAZOLE-6-CARBOXYLIC ACID DERIVATIVES AND SIMILAR COMPOUNDS AS GLP-1 MODULATORS FOR THE TREATMENT OF DIABETES JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN) 2026-01-28 EP disclosed
US-20260015348-A1 COMPOUNDS AS GLP-1R AGONISTS TERNS PHARMACEUTICALS INC (US) 2026-01-15 US disclosed
EP-4660194-A1 SALT AND CRYSTAL FORM OF CYCLOALKENE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF Jiangsu Hansoh Pharmaceutical Group Co., Ltd. (CN) 2025-12-10 EP disclosed
US-12479845-B2 Imidazopyridine derivative compounds and use of same HANMI PHARM. CO., LTD. (KR) 2025-11-25 US disclosed
US-12473279-B2 Fused imidazole derivative, preparation method therefor, and medical use thereof JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2025-11-18 US disclosed
US-20250346599-A1 TRICYCLIC PHTHALAZINONE PARP INHIBITORS AND METHODS OF USE VALO HEALTH INC (US) 2025-11-13 US disclosed
US-20250340544-A1 GLP-1 Receptor Agonists and Uses Thereof PFIZER INC. (US) 2025-11-06 US disclosed
US-5863947-A Phenylglycine derivatives useful for treating disorders of the central nervous system ELI LILLY AND COMPANY LIMITED (GB) 1999-01-26 US disclosed
CN-1202893-A Novel isoxazoline and isoxazole fibrinogen receptor antagonists DU PONT MERCK PHARMA (US) 1998-12-23 CN disclosed
US-5849736-A Isoxazoline and isoxazole fibrinogen receptor antagonists THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1998-12-15 US disclosed
WO-1998016526-A1 TETRAHYDRO-6H-PYRAZINO[1,2-B]ISOQUINOLINE 1,4-DIONES AS APOPROTEIN B-100 INHIBITORS GLAXO GROUP LIMITED (GB) 1998-04-23 WO disclosed
EP-0832076-A1 NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1998-04-01 EP disclosed
EP-0807621-A1 Derivatives of phenylglycine and use thereof as pharmaceuticals LILLY INDUSTRIES LIMITED (GB) 1997-11-19 EP disclosed
WO-1996038426-A1 NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-12-05 WO disclosed
EP-0730590-A1 NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-09-11 EP disclosed
WO-1995014683-A1 NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-06-01 WO disclosed
US-4784471-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015348-A1 COMPOUNDS AS GLP-1R AGONISTS GLP1R, GIPR, GCGR RAD51 3403/4885CA1 1470/4885CA2 602/4885
US-20250340544-A1 GLP-1 Receptor Agonists and Uses Thereof GLP1R, GIPR, GCGR RAD51 4812/4885CA1 3447/4885CA2 3222/4885
US-12473279-B2 Fused imidazole derivative, preparation method therefor, and medical use thereof GLP1R, GIPR, VIP RAD51 4461/4885CA1 4676/4885CA2 4204/4885
US-12479845-B2 Imidazopyridine derivative compounds and use of same KDM1A, KDM1B, KDM2A RAD51 4338/4885CA1 3423/4885CA2 1873/4885
US-12611401-B2 Combinations comprising benzodioxol as GLP-1R agonists for use in the treatment of NASH/NAFLD and related diseases GLP1R, GCKR, GPR119 RAD51 4560/4885CA1 4519/4885CA2 2281/4885
US-20250346599-A1 TRICYCLIC PHTHALAZINONE PARP INHIBITORS AND METHODS OF USE PARP1, PARP2, PARP3 RAD51 102/4885CA1 2883/4885CA2 1896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.