SCHEMBL29956543

SCHEMBL29956543

OB(O)c1cc(F)ccc1CSCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
RAB9A P51151 4/20 0.41
POLB P06746 3/20 0.41
TP53 P04637 3/20 0.39
LMNA P02545 5/20 0.39
MAPT P10636 4/20 0.39
TSHR P16473 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
LIPE Q05469 1/20 0.37
CYP2C19 P33261 1/20 0.36
PKM P14618 1/20 0.36
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CXCR2 P25025 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29952361 0.76 LIPE (0.47) ALDH1A1RAB9APOLBTP53LMNA
SCHEMBL29956910 0.76 ALDH1A1 (0.41) ALDH1A1RAB9APOLBMAPTSMN1; SMN2
SCHEMBL29951557 0.75 RAB9A (0.43) ALDH1A1RAB9APOLBTP53LMNA
SCHEMBL29950694 0.75 CXCR2 (0.40) ALDH1A1RAB9APOLBMAPTSMN1; SMN2
Methyl Alcohol SCHEMBL29261078 0.74 CYP2C19 (0.56) ALDH1A1RAB9ATP53LMNAMAPT
SCHEMBL29956655 0.74 CXCR2 (0.40) ALDH1A1RAB9APOLBLMNAMAPT
SCHEMBL29955289 0.73 CXCR2 (0.39) ALDH1A1RAB9ALMNASMN1; SMN2NPC1
SCHEMBL2560549 0.72 CXCR2 (0.43) RAB9ATP53LMNAMAPTSMN1; SMN2
SCHEMBL902030 0.71 IDO1 (0.34) SMN1; SMN2LIPEKDM4E
SCHEMBL15330371 0.70 TAAR1 (0.45) ALDH1A1LMNAMAPTSMN1; SMN2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed