Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.38 |
| ▸ | ABAT | P80404 | 2/20 | 0.38 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | UNG | P13051 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6928478 | 1.00 | KDM4E (0.41) | KDM4EPTGS2RAB9ACES2CES1 | |
| SCHEMBL31749296 | 0.85 | MAOB (0.43) | KDM4EPTGS2RAB9ACES2CES1 | |
| SCHEMBL15241305 | 0.85 | MAOB (0.43) | KDM4EPTGS2RAB9ACES2CES1 | |
| SCHEMBL281844 | 0.83 | KDM4E (0.39) | KDM4EPTGS2RAB9ACES2CES1 | |
| SCHEMBL5032374 | 0.83 | CES2 (0.38) | PTGS2CES2CES1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1715824 | 0.82 | ALDH1A1 (0.47) | KDM4EPTGS2RAB9ACES2CES1 | |
| SCHEMBL9958266 | 0.82 | KDM4E (0.45) | KDM4EPTGS2RAB9AALDH1A1ALDH5A1 | |
| SCHEMBL12954647 | 0.81 | DGAT1 (0.43) | KDM4EPTGS2RAB9ACES2CES1 | |
| SCHEMBL16579784 | 0.81 | ALDH1A1 (0.41) | KDM4EPTGS2RAB9ACES2CES1 | |
| SCHEMBL2045743 | 0.80 | ERN1 (0.46) | KDM4EPTGS2RAB9ACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |