Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.53 |
| ▸ | ABAT | P80404 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341936 | 1.00 | APEX1 (0.66) | APEX1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL3780489 | 0.84 | ALDH1A1 (0.56) | APEX1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL13858850 | 0.83 | ALDH1A1 (0.60) | APEX1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL396790 | 0.81 | MAPT (0.74) | APEX1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL11261243 | 0.79 | APEX1 (0.69) | APEX1ALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14235422 | 0.79 | APEX1 (0.69) | APEX1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL12656279 | 0.79 | APEX1 (0.69) | APEX1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL30538001 | 0.79 | APEX1 (0.69) | APEX1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL13220796 | 0.79 | HPGD (0.73) | APEX1ALDH1A1HPGDCYP1A2CYP3A4 | |
| SCHEMBL6512918 | 0.78 | ALDH5A1 (0.61) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |