SCHEMBL6512918

SCHEMBL6512918

O=Cc1ccc(SSc2ccc(C=O)cc2[N+](=O)[O-])c([N+](=O)[O-])c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH5A1 P51649 1/20 0.61
ABAT P80404 1/20 0.61
VCAM1 P19320 1/20 0.61
ALDH1A1 P00352 7/20 0.60
MAPT P10636 6/20 0.51
ALDH3A1 P30838 2/20 0.51
ALDH1A3 P47895 1/20 0.51
MEN1 O00255 6/20 0.51
KMT2A Q03164 6/20 0.51
HPGD P15428 4/20 0.51
HTT P42858 3/20 0.51
L3MBTL1 Q9Y468 1/20 0.48
XDH P47989 1/20 0.47
LMNA P02545 2/20 0.46
THRB P10828 1/20 0.46
TXNRD1 Q16881 1/20 0.46
TXNRD3 Q86VQ6 1/20 0.46
TXNRD2 Q9NNW7 1/20 0.46
NPSR1 Q6W5P4 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27858572 0.86 ALDH1A1 (0.57) ALDH5A1ABATVCAM1ALDH1A1MAPT
SCHEMBL5913764 0.86 ALDH1A1 (0.61) ALDH5A1ABATVCAM1ALDH1A1MAPT
SCHEMBL5913415 0.82 ALDH1A1 (0.57) ALDH5A1ABATVCAM1ALDH1A1MAPT
SCHEMBL1466944 0.80 ALDH5A1 (0.69) ALDH5A1ABATVCAM1ALDH1A1MAPT
SCHEMBL31484716 0.80 ALDH5A1 (0.69) ALDH5A1ABATVCAM1ALDH1A1MAPT
SCHEMBL6058010 0.78 ALDH1A1 (0.60) ALDH5A1ABATVCAM1ALDH1A1MAPT
SCHEMBL6930035 0.78 PLA2G4A (0.69) ALDH5A1ABATVCAM1ALDH1A1MAPT
SCHEMBL5341936 0.78 APEX1 (0.66) ALDH5A1ABATVCAM1ALDH1A1MAPT
SCHEMBL18376679 0.78 PDE7A (0.62) ALDH5A1ABATVCAM1ALDH1A1MAPT
SCHEMBL29956685 0.78 APEX1 (0.66) ALDH5A1ABATVCAM1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-3329971-A1 GOLF BALL Dunlop Sports Co., Ltd. (JP) 2018-06-06 EP disclosed
US-20130005506-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
CN-102526995-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
CN-102526997-A Golf ball SRI SPORTS LTD 2012-07-04 CN disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
CN-102485294-A Golf ball SRI SPORTS LTD 2012-06-06 CN disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed