Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 8/20 | 0.54 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315036 | 0.79 | KDM4E (0.35) | ERN1KDM4ECCR1CCR5CCR8 | |
| SCHEMBL6626617 | 0.78 | ERN1 (0.46) | ERN1SRCKDM4ECCR1CCR5 | |
| SCHEMBL29952796 | 0.78 | ERN1 (0.46) | ERN1SRCKDM4ECCR1CCR5 | |
| SCHEMBL2851214 | 0.75 | ALDH1A1 (0.47) | ERN1SRCKDM4ECCR1CCR5 | |
| SCHEMBL4640515 | 0.75 | ERN1 (0.43) | ERN1SRCKDM4ECCR1CCR5 | |
| SCHEMBL20124974 | 0.75 | NOS3 (0.54) | ERN1SRCKDM4ECCR1CCR5 | |
| SCHEMBL29955266 | 0.75 | ERN1 (0.43) | ERN1SRCKDM4ECCR1CCR5 | |
| SCHEMBL29954957 | 0.75 | ALDH1A1 (0.47) | ERN1SRCKDM4ECCR1CCR5 | |
| SCHEMBL14115886 | 0.75 | ERN1 (0.48) | ERN1OPRK1ALDH1A1LMNAKMT2A | |
| SCHEMBL8364837 | 0.75 | ERN1 (0.34) | ERN1KDM4EALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |