Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952427 | 0.86 | EPHX2 (0.40) | GAAUSP2EPHX2MEN1KMT2A | |
| SCHEMBL29955806 | 0.79 | CACNB4 (0.41) | GAAPIM1PIM2 | |
| SCHEMBL29954713 | 0.79 | HTR7 (0.36) | MEN1KMT2APIM1PIM2MAPT | |
| SCHEMBL29957172 | 0.79 | CA2 (0.43) | PIM1PIM2ALDH1A1 | |
| SCHEMBL24112743 | 0.77 | PGR (0.46) | GAAUSP2EPHX2TSHRMMP12 | |
| SCHEMBL13091038 | 0.77 | PGR (0.46) | GAAUSP2EPHX2TSHRMMP12 | |
| SCHEMBL16997522 | 0.76 | USP2 (0.36) | GAAUSP2EPHX2TSHRMEN1 | |
| SCHEMBL19563004 | 0.75 | GAA (0.40) | GAAUSP2TSHRMEN1KMT2A | |
| SCHEMBL21637687 | 0.75 | USP2 (0.38) | GAAUSP2EPHX2TSHRMEN1 | |
| SCHEMBL1101964 | 0.74 | IDO1 (0.47) | GAAMEN1KMT2ACREBBPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |