Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | MPL | P40238 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953626 | 0.86 | ALDH1A1 (0.37) | EPHX2APPTSHRGAAKDM4E | |
| SCHEMBL6500895 | 0.80 | GPR3 (0.42) | EPHX2EPAS1GAAKDM4EALDH1A1 | |
| SCHEMBL29377196 | 0.79 | PTGDR2 (0.51) | EPHX2EPAS1TSHRALDH1A1POLB | |
| SCHEMBL21266933 | 0.79 | ALDH1A1 (0.41) | EPHX2APPEPAS1TSHRGAA | |
| SCHEMBL26111715 | 0.79 | EPHX2 (0.38) | EPHX2APPEPAS1TSHRGAA | |
| SCHEMBL32682731 | 0.79 | ERN1 (0.47) | EPAS1KDM4EALDH1A1TDP1PKM | |
| SCHEMBL408055 | 0.79 | PTGDR2 (0.51) | EPHX2EPAS1TSHRALDH1A1POLB | |
| SCHEMBL30134318 | 0.79 | EPHX2 (0.38) | EPHX2APPEPAS1TSHRGAA | |
| SCHEMBL20303480 | 0.79 | ERN1 (0.47) | EPAS1KDM4EALDH1A1TDP1PKM | |
| SCHEMBL9367414 | 0.77 | GAA (0.40) | EPHX2APPTSHRGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |