Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654413 | 0.86 | POLB (0.47) | HTTLMNAALDH1A1ENPP2MEN1 | |
| SCHEMBL16654669 | 0.79 | HTT (0.41) | HTTLMNAALDH1A1ENPP2MEN1 | |
| SCHEMBL23388743 | 0.78 | PLAU (0.39) | ALDH1A1ENPP2HPGDMAPTTDP1 | |
| SCHEMBL5623456 | 0.78 | TSHR (0.52) | HTTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL3319802 | 0.78 | ALDH1A1 (0.41) | HTTLMNAALDH1A1ENPP2HPGD | |
| SCHEMBL8408406 | 0.77 | LMNA (0.47) | HTTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL6724121 | 0.77 | ALDH1A1 (0.44) | HTTLMNAALDH1A1ENPP2MEN1 | |
| SCHEMBL12681500 | 0.76 | CYP1A2 (0.50) | HTTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL17465565 | 0.76 | TSHR (0.34) | HTTLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2316275 | 0.76 | ENPP2 (0.60) | LMNAALDH1A1ENPP2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |