Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31177244 | 0.78 | LMNA (0.34) | KMT2A | |
| SCHEMBL25589550 | 0.78 | LMNA (0.34) | KMT2A | |
| SCHEMBL9591 | 0.78 | QPCT (0.37) | KMT2ACYP1A2METAP2 | |
| SCHEMBL7891452 | 0.75 | NUDT1 (0.44) | NUDT1KMT2ACYP1A2METAP2AURKB | |
| SCHEMBL29955721 | 0.75 | DHFR (0.38) | DHFR | |
| SCHEMBL2955132 | 0.74 | HPGD (0.38) | KMT2ACYP1A2 | |
| SCHEMBL24456358 | 0.74 | RXFP1 (0.39) | NUDT1DHFR | |
| SCHEMBL31631823 | 0.74 | NUDT1 (0.59) | NUDT1KMT2AP2RX3P2RX2CYP1A2 | |
| SCHEMBL4055122 | 0.74 | NUDT1 (0.59) | NUDT1KMT2AP2RX3P2RX2CYP1A2 | |
| SCHEMBL29956361 | 0.74 | RXFP1 (0.39) | NUDT1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |