SCHEMBL29956837

SCHEMBL29956837

O=C(O)c1nc(CO)c[nH]1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.33
LMNA P02545 1/20 0.32
CCR1 P32246 1/20 0.31
CGAS Q8N884 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300079 0.82 HCAR2 (0.35) HCAR2LMNACGAS
SCHEMBL12457457 0.82 HASPIN (0.30) CCR1
SCHEMBL5989125 0.82 MAOA (0.33) LMNACGAS
SCHEMBL20744170 0.79 BRD4 (0.33)
SCHEMBL2522318 0.77 GRN (0.37)
SCHEMBL15284409 0.77 HCAR2 (0.42) HCAR2LMNA
SCHEMBL6975840 0.77 NPSR1 (0.38) LMNANPSR1
SCHEMBL949037 0.76 BRD4 (0.43) HCAR2LMNA
SCHEMBL9322943 0.76 HCAR2 (0.44) HCAR2
SCHEMBL7866907 0.74 HRH4 (0.35) LMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed