SCHEMBL29956846

SCHEMBL29956846

COc1c(Cl)ccc(B(O)O)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TUBB4A P04350 3/20 0.38
TUBB P07437 3/20 0.38
TUBA3C P0DPH7 3/20 0.38
TUBA1B P68363 3/20 0.38
TUBA4A P68366 3/20 0.38
TUBB4B P68371 3/20 0.38
TUBB3 Q13509 3/20 0.38
TUBB2A Q13885 3/20 0.38
TUBB8 Q3ZCM7 3/20 0.38
TUBA3E Q6PEY2 3/20 0.38
TUBA1A Q71U36 3/20 0.38
TUBA1C Q9BQE3 3/20 0.38
TUBB6 Q9BUF5 3/20 0.38
TUBB2B Q9BVA1 3/20 0.38
TUBB1 Q9H4B7 3/20 0.38
ENPP2 Q13822 2/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1224743 1.00 ALDH1A1 (0.46) ALDH1A1KDM4EHSD17B10TUBB4ATUBB
SCHEMBL3839073 0.80 TUBB4A (0.36) ALDH1A1KDM4EHSD17B10TUBB4ATUBB
SCHEMBL31414966 0.80 TUBB4A (0.36) ALDH1A1KDM4EHSD17B10TUBB4ATUBB
SCHEMBL29951760 0.80 ALDH1A1 (0.43) ALDH1A1KDM4EHSD17B10TUBB4ATUBB
SCHEMBL718784 0.80 ALDH1A1 (0.43) ALDH1A1KDM4EHSD17B10TUBB4ATUBB
SCHEMBL29536407 0.77 ALDH1A1 (0.50) ALDH1A1KDM4EHSD17B10TUBB4ATUBB
SCHEMBL2355429 0.77 ALDH1A1 (0.50) ALDH1A1KDM4EHSD17B10TUBB4ATUBB
SCHEMBL21063368 0.76 ALDH1A1 (0.35) ALDH1A1KDM4ETUBB4ATUBBTUBA3C
SCHEMBL6651220 0.75 ENPP2 (0.47) ALDH1A1KDM4EHSD17B10ENPP2L3MBTL1
SCHEMBL3956911 0.75 CYP3A4 (0.46) ENPP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed