Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955450 | 0.85 | HTR2A (0.39) | CHRNB2CHRNA4LIPGDRD2DRD4 | |
| SCHEMBL29951134 | 0.80 | HTR2C (0.36) | LIPE | |
| SCHEMBL14394527 | 0.80 | CHRNB2 (0.45) | CHRNB2CHRNA4PRMT5WDR77CHRNB4 | |
| SCHEMBL4919386 | 0.78 | KDM4E (0.42) | PRMT5WDR77LIPGLIPENPSR1 | |
| SCHEMBL29958603 | 0.78 | KDM4E (0.42) | PRMT5WDR77LIPGLIPENPSR1 | |
| SCHEMBL14261316 | 0.76 | CHRNB2 (0.42) | CHRNB2CHRNA4PRMT5WDR77CHRNB4 | |
| SCHEMBL29957281 | 0.75 | LIPE (0.50) | LIPESRCCNR1ACHECNR2 | |
| SCHEMBL29952834 | 0.73 | LIPG (0.52) | LIPGLIPENPSR1 | |
| SCHEMBL12544470 | 0.73 | LIPG (0.52) | LIPGLIPENPSR1 | |
| SCHEMBL29953997 | 0.73 | LIPG (0.41) | LIPGDRD4LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |