Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CA4 | P22748 | 1/20 | 0.59 |
| ▸ | CA6 | P23280 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MYC | P01106 | 2/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1162134 | 1.00 | KDM4E (0.59) | KDM4ECA1CA2PTGS2CA12 | |
| SCHEMBL7295677 | 0.87 | PKM (0.57) | POLBMAPTHTTAKR1C3AKR1C2 | |
| SCHEMBL330378 | 0.85 | KDM4E (0.67) | KDM4ECA1CA2PTGS2CA12 | |
| SCHEMBL30268239 | 0.85 | KDM4E (0.67) | KDM4ECA1CA2PTGS2CA12 | |
| SCHEMBL458033 | 0.83 | CSNK2A1 (0.59) | KDM4ECA1CA2PTGS2CA12 | |
| SCHEMBL29955411 | 0.83 | CSNK2A1 (0.59) | KDM4ECA1CA2PTGS2CA12 | |
| SCHEMBL1561232 | 0.83 | KDM4E (0.59) | KDM4ECA1CA2PTGS2CA12 | |
| SCHEMBL6589349 | 0.83 | TSHR (0.50) | KDM4EGAAMYCAKR1C3AKR1C2 | |
| SCHEMBL10541064 | 0.83 | KDM4E (0.64) | KDM4ECA1CA2PTGS2CA12 | |
| SCHEMBL10546163 | 0.83 | KDM4E (0.64) | KDM4ECA1CA2PTGS2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106974-A1 | PRODRUG MOIETIES AND COMPOUNDS COMPRISING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-05-22 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |