Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4443752 | 0.96 | TSHR (0.62) | HTTTSHRRECQLKMT2ASMN1; SMN2 | |
| SCHEMBL29954605 | 0.92 | HTT (0.58) | HTTTSHRRECQLKMT2ASMN1; SMN2 | |
| SCHEMBL6411599 | 0.86 | L3MBTL1 (0.69) | HTTTSHRRECQLKMT2AL3MBTL1 | |
| SCHEMBL3758627 | 0.84 | ALDH1A1 (0.63) | HTTTSHRKMT2ASMN1; SMN2HPGD | |
| SCHEMBL29956307 | 0.84 | ALDH1A1 (0.63) | HTTTSHRKMT2ASMN1; SMN2HPGD | |
| SCHEMBL1743230 | 0.83 | ACHE (0.61) | HTTKMT2ASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL10720608 | 0.80 | TSHR (0.69) | HTTTSHRRECQLKMT2ASMN1; SMN2 | |
| SCHEMBL13162411 | 0.79 | HTT (0.96) | HTTKMT2AHPGDALDH1A1 | |
| SCHEMBL14825166 | 0.78 | HTT (1.00) | HTTKMT2AHPGDALDH1A1 | |
| SCHEMBL29940966 | 0.77 | HTT (0.62) | HTTTSHRRECQLKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |