Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364409 | 0.82 | MEN1 (0.50) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL8375135 | 0.81 | MEN1 (0.49) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL7368604 | 0.81 | LMNA (0.54) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL8375863 | 0.79 | MEN1 (0.47) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL28402173 | 0.78 | LMNA (0.61) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL8376699 | 0.78 | MEN1 (0.46) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL14566738 | 0.78 | ALDH1A1 (0.51) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL8376712 | 0.77 | HSD17B10 (0.66) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL8375140 | 0.76 | KDM6B (0.51) | LMNAL3MBTL1MEN1KMT2ATSHR | |
| SCHEMBL8374736 | 0.74 | KDM6B (0.51) | LMNAL3MBTL1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |