Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254051 | 0.83 | POLB (0.54) | POLBPKMGAAMETCYP2C19 | |
| SCHEMBL3316587 | 0.78 | CA1 (0.55) | POLBPKMGAACA1CA2 | |
| SCHEMBL28018957 | 0.78 | PKM (0.50) | POLBPKMGAACYP2C19ALDH1A1 | |
| SCHEMBL12419386 | 0.74 | CA2 (0.58) | PKMENPP2CA1CA2MGLL | |
| SCHEMBL28977118 | 0.71 | AKR1C3 (0.56) | POLBPKMGAAAKR1C3AKR1C1 | |
| SCHEMBL12266126 | 0.69 | PARL (0.43) | PKMENPP2CA1CA2CA4 | |
| SCHEMBL22558324 | 0.67 | CA2 (0.58) | POLBPKMCA1CA2CA12 | |
| SCHEMBL28392879 | 0.67 | POLB (0.40) | POLBPKMGAAMETCYP2C19 | |
| SCHEMBL540011 | 0.67 | NOTUM (0.58) | POLBENPP2GAAMGLLCA4 | |
| SCHEMBL30352605 | 0.66 | POLB (0.51) | POLBPKMGAAMETCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |