Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1853561 | 0.78 | CA2 (0.44) | NPC1MEN1KMT2AMAPTENPP2 | |
| SCHEMBL5038826 | 0.77 | CES2 (0.48) | NPC1MEN1KMT2AMAPTCES2 | |
| SCHEMBL9419202 | 0.77 | HTR7 (0.50) | HTR7NPC1MCL1 | |
| SCHEMBL29410296 | 0.77 | GSTP1 (0.52) | — | |
| SCHEMBL3686032 | 0.77 | GSTP1 (0.52) | — | |
| SCHEMBL19997905 | 0.77 | APP (0.36) | MCL1APPMAPTENPP2TLR8 | |
| SCHEMBL2932780 | 0.77 | CNR2 (0.44) | NPC1KMT2AMAPT | |
| SCHEMBL29956783 | 0.77 | CNR2 (0.44) | NPC1KMT2AMAPT | |
| SCHEMBL5987885 | 0.77 | MCL1 (0.47) | HTR7MCL1CREBBP | |
| SCHEMBL14508378 | 0.76 | CA2 (0.43) | NPC1MEN1KMT2AMAPTENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |