Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951119 | 0.91 | PIM1 (0.49) | KMT2AL3MBTL1PIM1PIM3PIM2 | |
| SCHEMBL18228108 | 0.85 | EPHX2 (0.43) | KMT2AL3MBTL1PIM1PIM3PIM2 | |
| SCHEMBL29952159 | 0.85 | PIM1 (0.44) | KMT2AL3MBTL1PIM1PIM3PIM2 | |
| SCHEMBL20806445 | 0.82 | KMT2A (0.52) | KMT2AL3MBTL1PIM1PIM3PIM2 | |
| SCHEMBL2558065 | 0.81 | UNG (0.41) | KMT2A | |
| SCHEMBL24541862 | 0.79 | PDE10A (0.43) | KMT2AL3MBTL1PIM1PIM3PIM2 | |
| SCHEMBL30409365 | 0.79 | GPR119 (0.43) | GPR119NR1H2NR1H3 | |
| SCHEMBL24215992 | 0.79 | GPR119 (0.43) | GPR119NR1H2NR1H3 | |
| SCHEMBL30409181 | 0.79 | GPR119 (0.43) | GPR119NR1H2NR1H3 | |
| SCHEMBL18228499 | 0.78 | USP30 (0.43) | KMT2AL3MBTL1PIM1PIM3PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |