Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 5/20 | 0.54 |
| ▸ | NOS2 | P35228 | 5/20 | 0.54 |
| ▸ | NOS1 | P29475 | 3/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27018478 | 1.00 | NOS3 (0.54) | NOS3NOS2NOS1MAP4K4KDM4E | |
| SCHEMBL16754314 | 0.78 | CYP2A6 (0.36) | CA2LPLLIPG | |
| SCHEMBL18895037 | 0.77 | CA2 (0.34) | CA2LPLLIPGENPP2 | |
| SCHEMBL15774846 | 0.76 | CA2 (0.31) | CA2LPLLIPG | |
| SCHEMBL29958107 | 0.76 | CA2 (0.31) | CA2LPLLIPG | |
| SCHEMBL26916859 | 0.76 | KDR (0.41) | NOS3NOS2NOS1PDGFRBKDR | |
| SCHEMBL25346943 | 0.75 | PDGFRB (0.40) | NOS3NOS2NOS1KDM4EALDH1A1 | |
| SCHEMBL393995 | 0.75 | CHRNB2 (0.33) | ALDH1A1CA2LPLLIPGENPP2 | |
| SCHEMBL18228109 | 0.75 | UHRF1 (0.34) | NOS3NOS2NOS1KDM4EALDH1A1 | |
| SCHEMBL29775155 | 0.75 | UHRF1 (0.34) | NOS3NOS2NOS1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |