Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.32 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.32 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2279409 | 0.82 | PTPN1 (0.55) | PTPN1KMT2AENPP2KDM4E | |
| SCHEMBL3411399 | 0.82 | L3MBTL1 (0.45) | KMT2AENPP2KDM4EL3MBTL1GAA | |
| SCHEMBL6651220 | 0.80 | ENPP2 (0.47) | KMT2AENPP2KDM4EL3MBTL1GAA | |
| SCHEMBL29955198 | 0.79 | ENPP2 (0.53) | PTPN1KMT2AENPP2KDM4EL3MBTL1 | |
| SCHEMBL23350067 | 0.79 | PTPN1 (0.42) | PTPN1ENPP2LIPEORAI1ORAI2 | |
| SCHEMBL3982711 | 0.78 | KDM4E (0.45) | KMT2AENPP2KDM4EL3MBTL1GAA | |
| SCHEMBL2574218 | 0.77 | SCN4A (0.38) | KMT2AENPP2KDM4ELIPE | |
| SCHEMBL29958452 | 0.77 | LIPE (0.58) | KMT2AENPP2KDM4EL3MBTL1MAPT | |
| SCHEMBL5840798 | 0.76 | EGFR (0.41) | PTPN1ENPP2KDM4EL3MBTL1GAA | |
| SCHEMBL31454297 | 0.75 | KMT2A (0.38) | PTPN1KMT2AKDM4EL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |