Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951882 | 0.88 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1OPRD1LMNAALDH1A1 | |
| SCHEMBL950219 | 0.86 | RIPK1 (0.34) | — | |
| SCHEMBL15663058 | 0.85 | MAPT (0.34) | — | |
| SCHEMBL875274 | 0.82 | KMT2A (0.40) | KCNH2ALDH1A1 | |
| SCHEMBL29954754 | 0.82 | KMT2A (0.40) | KCNH2ALDH1A1 | |
| SCHEMBL29956454 | 0.81 | CYP3A4 (0.47) | HSP90AA1HSP90AB1ALDH1A1TSHRHPGD | |
| SCHEMBL4037887 | 0.81 | CYP3A4 (0.47) | HSP90AA1HSP90AB1ALDH1A1TSHRHPGD | |
| SCHEMBL6068880 | 0.80 | CES2 (0.55) | HSP90AA1HSP90AB1OPRD1CYP2D6KCNH2 | |
| SCHEMBL21508521 | 0.79 | HSP90AB1 (0.43) | HSP90AB1KCNH2ALDH1A1TSHRHPGD | |
| SCHEMBL471668 | 0.79 | HPGD (0.51) | HSP90AA1HSP90AB1OPRD1CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |