Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875274 | 1.00 | KMT2A (0.40) | KMT2ASMN1; SMN2L3MBTL1ALDH1A1ERN1 | |
| SCHEMBL15465164 | 0.86 | AR (0.45) | KMT2ASMN1; SMN2L3MBTL1ALDH1A1ERN1 | |
| SCHEMBL950219 | 0.84 | RIPK1 (0.34) | KMT2ACES2CES1PIK3CAMTOR | |
| SCHEMBL226335 | 0.84 | PIK3CA (0.39) | CES2CES1PIK3CAMTOR | |
| SCHEMBL3788331 | 0.84 | ALDH1A1 (0.40) | KMT2ASMN1; SMN2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL29957503 | 0.82 | HSP90AA1 (0.40) | ALDH1A1KCNH2 | |
| SCHEMBL22575311 | 0.81 | ALDH1A1 (0.38) | KMT2ASMN1; SMN2L3MBTL1ALDH1A1ERN1 | |
| SCHEMBL30963904 | 0.80 | MAOB (0.43) | ALDH1A1CES2CES1 | |
| SCHEMBL1319282 | 0.80 | MAOB (0.43) | ALDH1A1CES2CES1 | |
| SCHEMBL15663058 | 0.80 | MAPT (0.34) | CES2CES1MAP2K1PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |