Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13609687 | 1.00 | GSK3B (0.47) | GSK3BAXLHTR2AHTR2CHTR2B | |
| SCHEMBL29956078 | 0.86 | AXL (0.45) | GSK3BAXLJAK2PDPK1KDM4E | |
| SCHEMBL31423289 | 0.82 | GSK3B (0.47) | GSK3BAXLHTR2AHTR2CHTR2B | |
| SCHEMBL29953125 | 0.80 | KIF11 (0.47) | AXLJAK2PDPK1AURKAKDM4E | |
| SCHEMBL3534726 | 0.80 | KIF11 (0.47) | AXLJAK2PDPK1AURKAKDM4E | |
| SCHEMBL22889917 | 0.79 | GSK3B (0.49) | GSK3BAXLHTR2AHTR2CHTR2B | |
| SCHEMBL3538836 | 0.79 | PDPK1 (0.42) | PDPK1AURKAKDM4EGAAMEN1 | |
| SCHEMBL3541493 | 0.79 | FADS1 (0.45) | HTR2AJAK2GAAHPGDTDP1 | |
| SCHEMBL955512 | 0.79 | NOS1 (0.38) | GSK3BJAK2PDPK1AURKAPARP1 | |
| SCHEMBL3540306 | 0.79 | ITK (0.43) | HTR2AKDM4EGAAALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |