Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634488 | 1.00 | LOXL2 (0.46) | LOXL2CYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL1517135 | 0.85 | CYP1A2 (0.45) | CYP1A2TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL29954542 | 0.83 | TSHR (0.45) | CYP1A2TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL2555778 | 0.81 | CYP1A2 (0.42) | CYP1A2TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL16576663 | 0.78 | CYP1A2 (0.40) | CYP1A2TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL2062221 | 0.78 | LOXL2 (0.55) | LOXL2CYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL7253099 | 0.78 | TSHR (0.50) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL6691566 | 0.77 | GPR35 (0.56) | LOXL2CYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL11304556 | 0.77 | ALDH1A1 (0.61) | LOXL2CYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL28405139 | 0.77 | KMT2A (0.57) | CYP1A2ALDH1A1CYP3A4TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117270235-A | Contact lens having a lubricious coating thereon | 爱尔康公司 | 2023-12-22 | — | — | CN | claimed |
| CN-111566517-B | Contact lens having a lubricious coating thereon | 爱尔康公司 | 2023-11-10 | — | — | CN | claimed |
| CN-117270235-A | Contact lens having a lubricious coating thereon | 爱尔康公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-111566517-B | Contact lens having a lubricious coating thereon | 爱尔康公司 | 2023-11-10 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |