Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955180 | 0.90 | ERN1 (0.44) | ERN1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL13744875 | 0.90 | ERN1 (0.44) | ERN1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL25608282 | 0.86 | ERN1 (0.42) | ERN1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL29180725 | 0.86 | ERN1 (0.42) | ERN1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL8709932 | 0.79 | ACHE (0.52) | ERN1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL841371 | 0.79 | ALDH1A1 (0.46) | ERN1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL25295009 | 0.77 | ENPP2 (0.40) | ERN1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL28394894 | 0.77 | ENPP2 (0.40) | ERN1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL17376697 | 0.77 | ERN1 (0.48) | ERN1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL4889447 | 0.76 | ERN1 (0.43) | ERN1NPC1KDM4EMAP3K14TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709724-A1 | ANTICONVULSIVE COMPOUNDS AND USES THEREOF | Jazz Pharmaceuticals Research UK Limited (GB) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024236275-A1 | ANTICONVULSIVE COMPOUNDS AND USES THEREOF | JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (GB) | 2024-11-21 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |