Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 17/20 | 0.40 |
| ▸ | NOS1 | P29475 | 16/20 | 0.40 |
| ▸ | NOS3 | P29474 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300118 | 0.70 | CNR1 (0.45) | — | |
| SCHEMBL2555217 | 0.68 | APOL1 (0.34) | NOS2 | |
| SCHEMBL2561242 | 0.68 | APOL1 (0.40) | — | |
| SCHEMBL2557800 | 0.68 | ERN1 (0.34) | NOS2NOS1NOS3 | |
| SCHEMBL15331079 | 0.67 | PARP1 (0.35) | NOS2NOS1NOS3 | |
| SCHEMBL2561523 | 0.67 | ERN1 (0.33) | NOS2NOS1NOS3DYRK1A | |
| SCHEMBL2554074 | 0.66 | PIM1 (0.34) | — | |
| SCHEMBL2562293 | 0.66 | PTGS2 (0.36) | — | |
| SCHEMBL15331776 | 0.65 | KDM4E (0.42) | — | |
| SCHEMBL15332675 | 0.65 | KIF11 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |