Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CCR5 | P51681 | 1/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12260616 | 1.00 | CCR1 (0.52) | CCR1RAB9ACCR5METAP2PARP1 | |
| SCHEMBL13738312 | 0.76 | METAP2 (0.57) | CCR1RAB9ACCR5METAP2PARP1 | |
| SCHEMBL1699392 | 0.76 | CCR1 (0.50) | CCR1RAB9ACCR5METAP2PARP1 | |
| SCHEMBL29698786 | 0.76 | CCR1 (0.50) | CCR1RAB9ACCR5METAP2PARP1 | |
| SCHEMBL7449839 | 0.75 | CCR1 (0.61) | CCR1RAB9ACCR5METAP2PARP1 | |
| SCHEMBL29440934 | 0.75 | CCR1 (0.61) | CCR1RAB9ACCR5METAP2PARP1 | |
| SCHEMBL29652865 | 0.75 | RAB9A (0.37) | CCR1RAB9ACCR5METAP2KMT2A | |
| SCHEMBL114582 | 0.75 | RAB9A (0.37) | CCR1RAB9ACCR5METAP2KMT2A | |
| SCHEMBL29957732 | 0.74 | METAP2 (0.60) | CCR1RAB9ACCR5METAP2PARP1 | |
| SCHEMBL14988789 | 0.74 | METAP2 (0.60) | CCR1RAB9ACCR5METAP2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118715015-A | Selective PHD1 inhibitor compounds, compositions and methods of use | 阿克比治疗有限公司 | 2024-09-27 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |